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Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome

Brain iron deficiency (BID) constitutes a primary pathophysiological mechanism in restless legs syndrome (RLS). BID in rodents has been widely used as an animal model of RLS, since it recapitulates key neurochemical changes reported in RLS patients and shows an RLS-like behavioral phenotype. Previou...

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Detalles Bibliográficos
Autores principales: Rodrigues, Matilde S., Ferreira, Samira G., Quiroz, César, Earley, Christopher J., García-Borreguero, Diego, Cunha, Rodrigo A., Ciruela, Francisco, Köfalvi, Attila, Ferré, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911604/
https://www.ncbi.nlm.nih.gov/pubmed/35268590
http://dx.doi.org/10.3390/molecules27051489