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Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome
Brain iron deficiency (BID) constitutes a primary pathophysiological mechanism in restless legs syndrome (RLS). BID in rodents has been widely used as an animal model of RLS, since it recapitulates key neurochemical changes reported in RLS patients and shows an RLS-like behavioral phenotype. Previou...
Autores principales: | Rodrigues, Matilde S., Ferreira, Samira G., Quiroz, César, Earley, Christopher J., García-Borreguero, Diego, Cunha, Rodrigo A., Ciruela, Francisco, Köfalvi, Attila, Ferré, Sergi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911604/ https://www.ncbi.nlm.nih.gov/pubmed/35268590 http://dx.doi.org/10.3390/molecules27051489 |
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