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Activation of the Nrf2 Pathway as a Therapeutic Strategy for ALS Treatment
Amyotrophic lateral sclerosis is a progressive and fatal disease that causes motoneurons degeneration and functional impairment of voluntary muscles, with limited and poorly efficient therapies. Alterations in the Nrf2-ARE pathway are associated with ALS pathology and result in aberrant oxidative st...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911691/ https://www.ncbi.nlm.nih.gov/pubmed/35268572 http://dx.doi.org/10.3390/molecules27051471 |