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Integrated Machine Learning and Chemoinformatics-Based Screening of Mycotic Compounds against Kinesin Spindle ProteinEg5 for Lung Cancer Therapy

Among the various types of cancer, lung cancer is the second most-diagnosed cancer worldwide. The kinesin spindle protein, Eg5, is a vital protein behind bipolar mitotic spindle establishment and maintenance during mitosis. Eg5 has been reported to contribute to cancer cell migration and angiogenesi...

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Detalles Bibliográficos
Autores principales: Maiti, Priyanka, Sharma, Priyanka, Nand, Mahesha, Bhatt, Indra D., Ramakrishnan, Muthannan Andavar, Mathpal, Shalini, Joshi, Tushar, Pant, Ragini, Mahmud, Shafi, Simal-Gandara, Jesus, Alshehri, Sultan, Ghoneim, Mohammed M., Alruwaily, Maha, Awadh, Ahmed Abdullah Al, Alshahrani, Mohammed Merae, Chandra, Subhash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911701/
https://www.ncbi.nlm.nih.gov/pubmed/35268740
http://dx.doi.org/10.3390/molecules27051639