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Integrated Machine Learning and Chemoinformatics-Based Screening of Mycotic Compounds against Kinesin Spindle ProteinEg5 for Lung Cancer Therapy
Among the various types of cancer, lung cancer is the second most-diagnosed cancer worldwide. The kinesin spindle protein, Eg5, is a vital protein behind bipolar mitotic spindle establishment and maintenance during mitosis. Eg5 has been reported to contribute to cancer cell migration and angiogenesi...
Autores principales: | Maiti, Priyanka, Sharma, Priyanka, Nand, Mahesha, Bhatt, Indra D., Ramakrishnan, Muthannan Andavar, Mathpal, Shalini, Joshi, Tushar, Pant, Ragini, Mahmud, Shafi, Simal-Gandara, Jesus, Alshehri, Sultan, Ghoneim, Mohammed M., Alruwaily, Maha, Awadh, Ahmed Abdullah Al, Alshahrani, Mohammed Merae, Chandra, Subhash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911701/ https://www.ncbi.nlm.nih.gov/pubmed/35268740 http://dx.doi.org/10.3390/molecules27051639 |
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