Indole-Based Tubulin Inhibitors: Binding Modes and SARs Investigations

Tubulin inhibitors can interfere with normal cell mitosis and inhibit cell proliferation through interfering with the normal structure and function of microtubules, forming spindle filaments. Indole, as a privileged pharmacological skeleton, has been widely used in anti-cancer inhibitors. A variety...

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Detalles Bibliográficos
Autores principales: Tang, Sheng, Zhou, Zhihui, Jiang, Zhiyan, Zhu, Wufu, Qiao, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911766/
https://www.ncbi.nlm.nih.gov/pubmed/35268688
http://dx.doi.org/10.3390/molecules27051587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911766/
https://www.ncbi.nlm.nih.gov/pubmed/35268688
http://dx.doi.org/10.3390/molecules27051587

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