Synthesis and Evaluation of (11)C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography

Cancer cells require lipids to fulfill energetic, proliferative, and signaling requirements. Even though these cells can take up exogenous fatty acids, the majority exhibit a dependency on de novo fatty acid synthesis. Fatty acid synthase (FASN) is the rate-limiting enzyme in this process. Expressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelly, James M., Jeitner, Thomas M., Waterhouse, Nicole N., Qu, Wenchao, Linstad, Ethan J., Samani, Banafshe, Williams, Clarence, Nikolopoulou, Anastasia, Amor-Coarasa, Alejandro, DiMagno, Stephen G., Babich, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911806/
https://www.ncbi.nlm.nih.gov/pubmed/35268652
http://dx.doi.org/10.3390/molecules27051552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911806/
https://www.ncbi.nlm.nih.gov/pubmed/35268652
http://dx.doi.org/10.3390/molecules27051552

Ejemplares similares