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Intermolecular Mechanism and Dynamic Investigation of Avian Influenza H7N9 Virus’ Susceptibility to E119V-Substituted Peramivir–Neuraminidase Complex

The H7N9 virus attaches itself to the human cell receptor protein containing the polysaccharide that terminates with sialic acid. The mutation of neuraminidase at residue E119 has been explored experimentally. However, there is no adequate information on the substitution with E119V in peramivir at t...

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Detalles Bibliográficos
Autores principales: Mtambo, Sphamandla E., Ugbaja, Samuel C., Mushebenge, Aganze G., Abubakar, Bahijjahtu H., Ntuli, Mthobisi L., Kumalo, Hezekiel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911867/
https://www.ncbi.nlm.nih.gov/pubmed/35268741
http://dx.doi.org/10.3390/molecules27051640