Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines

In our continuing effort to develop effective anti-heroin vaccines as potential medications for the treatment of opioid use disorder, herein we present the design and synthesis of the haptens: 1-AmidoMorHap (1), 1-AmidoMorHap epimer (2), 1 Amido-DihydroMorHap (3), and 1 Amido-DihydroMorHap epimer (4...

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Detalles Bibliográficos
Autores principales: Sulima, Agnieszka, Li, Fuying, Morgan, Jeffrey Brian, Truong, Phong, Antoline, Joshua F. G., Oertel, Therese, Barrientos, Rodell C., Torres, Oscar B., Beck, Zoltan, Imler, Gregory H., Deschamps, Jeffrey R., Matyas, Gary R., Jacobson, Arthur E., Rice, Kenner C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911913/
https://www.ncbi.nlm.nih.gov/pubmed/35268659
http://dx.doi.org/10.3390/molecules27051553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911913/
https://www.ncbi.nlm.nih.gov/pubmed/35268659
http://dx.doi.org/10.3390/molecules27051553

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