An Orthogonal Synthetic Approach to Nonsymmetrical Bisazolyl 2,4,6-Trisubstituted Pyridines

A three-step synthetic route giving access to nonsymmetrical bisazolyl 2,4,6-trisubstituted pyridines with different substituents on the pyrazole, indazole, and pyridine heterocycles is described. From the readily available 4-bromo-2,6-difluoropyridine, both fluorine atoms allow for easy selective s...

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Detalles Bibliográficos
Autores principales: Gamonal Ruiz-Crespo, Arturo, Galán-Fernández, Laura, Martínez-Martín, Paloma, Rodríguez-Ubis, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911976/
https://www.ncbi.nlm.nih.gov/pubmed/35268847
http://dx.doi.org/10.3390/molecules27051746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911976/
https://www.ncbi.nlm.nih.gov/pubmed/35268847
http://dx.doi.org/10.3390/molecules27051746

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