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In Vitro and Computational Studies of Perezone and Perezone Angelate as Potential Anti-Glioblastoma Multiforme Agents

Glioblastoma multiforme (GBM) represents the most malignant type of astrocytoma, with a life expectancy of two years. It has been shown that Poly (ADP-ribose) polymerase 1 (PARP-1) protein is over-expressed in GBM cells, while its expression in healthy tissue is low. In addition, perezone, a phyto-c...

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Detalles Bibliográficos
Autores principales: Hernández-Rodríguez, Maricarmen, Mendoza Sánchez, Pablo I., Martínez, Joel, Macías Pérez, Martha E., Rosales Cruz, Erika, Żołek, Teresa, Maciejewska, Dorota, Miranda Ruvalcaba, René, Mera Jiménez, Elvia, Nicolás-Vázquez, María I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911992/
https://www.ncbi.nlm.nih.gov/pubmed/35268667
http://dx.doi.org/10.3390/molecules27051565