Oxidative Stress and Cancer Heterogeneity Orchestrate NRF2 Roles Relevant for Therapy Response

Oxidative stress and its end-products, such as 4-hydroxynonenal (HNE), initiate activation of the Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)/Kelch Like ECH Associated Protein 1 (KEAP1) signaling pathway that plays a crucial role in the maintenance of cellular redox homeostasis. However, an i...

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Detalles Bibliográficos
Autores principales: Gall Trošelj, Koraljka, Tomljanović, Marko, Jaganjac, Morana, Matijević Glavan, Tanja, Čipak Gašparović, Ana, Milković, Lidija, Borović Šunjić, Suzana, Buttari, Brigitta, Profumo, Elisabetta, Saha, Sarmistha, Saso, Luciano, Žarković, Neven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912061/
https://www.ncbi.nlm.nih.gov/pubmed/35268568
http://dx.doi.org/10.3390/molecules27051468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912061/
https://www.ncbi.nlm.nih.gov/pubmed/35268568
http://dx.doi.org/10.3390/molecules27051468

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