TNF-α induces Claudin-1 expression in renal tubules in Alport mice

Claudin-1 (CL-1) is responsible for the paracellular barrier function of glomerular parietal epithelial cells (PEC) in kidneys, but the role of CL-1 in proximal tubules remains to be elucidated. In this study, to evaluate CL-1 as a potential therapeutic drug target for chronic kidney disease, we inv...

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Detalles Bibliográficos
Autores principales: Iida, Manami, Ohtomo, Shuichi, Wada, Naoko A., Ueda, Otoya, Tsuboi, Yoshinori, Kurata, Atsuo, Jishage, Kou-ichi, Horiba, Naoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912176/
https://www.ncbi.nlm.nih.gov/pubmed/35271660
http://dx.doi.org/10.1371/journal.pone.0265081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912176/
https://www.ncbi.nlm.nih.gov/pubmed/35271660
http://dx.doi.org/10.1371/journal.pone.0265081

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