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TNF-α induces Claudin-1 expression in renal tubules in Alport mice
Claudin-1 (CL-1) is responsible for the paracellular barrier function of glomerular parietal epithelial cells (PEC) in kidneys, but the role of CL-1 in proximal tubules remains to be elucidated. In this study, to evaluate CL-1 as a potential therapeutic drug target for chronic kidney disease, we inv...
Autores principales: | Iida, Manami, Ohtomo, Shuichi, Wada, Naoko A., Ueda, Otoya, Tsuboi, Yoshinori, Kurata, Atsuo, Jishage, Kou-ichi, Horiba, Naoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912176/ https://www.ncbi.nlm.nih.gov/pubmed/35271660 http://dx.doi.org/10.1371/journal.pone.0265081 |
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