iPSC reprogramming-mediated aneuploidy correction in autosomal trisomy syndromes

Trisomy 21, 18, and 13 are the major autosomal aneuploidy disorders in humans. They are mostly derived from chromosome non-disjunction in maternal meiosis, and the extra trisomic chromosome can cause several congenital malformations. Various genes on the trisomic chromosomes are intricately involved...

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Detalles Bibliográficos
Autores principales: Akutsu, Silvia Natsuko, Miyamoto, Tatsuo, Oba, Daiju, Tomioka, Keita, Ochiai, Hiroshi, Ohashi, Hirofumi, Matsuura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912248/
https://www.ncbi.nlm.nih.gov/pubmed/35271616
http://dx.doi.org/10.1371/journal.pone.0264965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912248/
https://www.ncbi.nlm.nih.gov/pubmed/35271616
http://dx.doi.org/10.1371/journal.pone.0264965

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