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The Association between Accumulation of Toxic Advanced Glycation End-Products and Cytotoxic Effect in MC3T3-E1 Cells

In diabetic patients, the metabolism of excess glucose increases the toxicity of the aldehyde group of sugar. Aldehydes, including glyceraldehyde (GA), react with intracellular proteins to form advanced glycation end-products (AGEs), which deteriorate bone quality and cause osteoporosis. One of the...

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Detalles Bibliográficos
Autores principales: Sakasai-Sakai, Akiko, Takata, Takanobu, Takeuchi, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912344/
https://www.ncbi.nlm.nih.gov/pubmed/35267965
http://dx.doi.org/10.3390/nu14050990