Neohesperidin Dihydrochalcone and Neohesperidin Dihydrochalcone-O-Glycoside Attenuate Subcutaneous Fat and Lipid Accumulation by Regulating PI3K/AKT/mTOR Pathway In Vivo and In Vitro

Neohesperidin dihydrochalcone (NHDC), a semi-natural compound from bitter orange, is an intense sweetener. The anti-obesity effects of NHDC and its glycosidic compound, NHDC-O-glycoside (GNHDC), were investigated. C57BLKS/J db/db mice were supplemented with NHDC or GNHDC (100 mg/kg b.w.) for 4 weeks...

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Detalles Bibliográficos
Autores principales: Kwon, Minseo, Kim, Yerin, Lee, Jihye, Manthey, John A., Kim, Yang, Kim, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912486/
https://www.ncbi.nlm.nih.gov/pubmed/35268062
http://dx.doi.org/10.3390/nu14051087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912486/
https://www.ncbi.nlm.nih.gov/pubmed/35268062
http://dx.doi.org/10.3390/nu14051087

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