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In heart failure reactivation of RNA-binding proteins is associated with the expression of 1,523 fetal-specific isoforms

Reactivation of fetal-specific genes and isoforms occurs during heart failure. However, the underlying molecular mechanisms and the extent to which the fetal program switch occurs remains unclear. Limitations hindering transcriptome-wide analyses of alternative splicing differences (i.e. isoform swi...

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Detalles Bibliográficos
Autores principales: D’Antonio, Matteo, Nguyen, Jennifer P., Arthur, Timothy D., Matsui, Hiroko, Donovan, Margaret K. R., D’Antonio-Chronowska, Agnieszka, Frazer, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912908/
https://www.ncbi.nlm.nih.gov/pubmed/35226669
http://dx.doi.org/10.1371/journal.pcbi.1009918