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In heart failure reactivation of RNA-binding proteins is associated with the expression of 1,523 fetal-specific isoforms
Reactivation of fetal-specific genes and isoforms occurs during heart failure. However, the underlying molecular mechanisms and the extent to which the fetal program switch occurs remains unclear. Limitations hindering transcriptome-wide analyses of alternative splicing differences (i.e. isoform swi...
Autores principales: | D’Antonio, Matteo, Nguyen, Jennifer P., Arthur, Timothy D., Matsui, Hiroko, Donovan, Margaret K. R., D’Antonio-Chronowska, Agnieszka, Frazer, Kelly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912908/ https://www.ncbi.nlm.nih.gov/pubmed/35226669 http://dx.doi.org/10.1371/journal.pcbi.1009918 |
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