Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside

BACKGROUND: To accelerate the progress towards onchocerciasis elimination, a macrofilaricidal drug that kills the adult parasite is urgently needed. Emodepside has shown macrofilaricidal activity against a variety of nematodes and is currently under clinical development for the treatment of onchocer...

Descripción completa

Detalles Bibliográficos
Autores principales: Assmus, Frauke, Hoglund, Richard M., Monnot, Frédéric, Specht, Sabine, Scandale, Ivan, Tarning, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912909/
https://www.ncbi.nlm.nih.gov/pubmed/35271567
http://dx.doi.org/10.1371/journal.pntd.0010219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912909/
https://www.ncbi.nlm.nih.gov/pubmed/35271567
http://dx.doi.org/10.1371/journal.pntd.0010219

Ejemplares similares