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Physiological Considerations for Modeling in vivo Antibody-Target Interactions
The number of therapeutic antibodies in development pipelines is increasing rapidly. Despite superior success rates relative to small molecules, therapeutic antibodies still face many unique development challenges. There is often a translational gap from their high target affinity and specificity to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912916/ https://www.ncbi.nlm.nih.gov/pubmed/35281913 http://dx.doi.org/10.3389/fphar.2022.856961 |