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Physiological Considerations for Modeling in vivo Antibody-Target Interactions

The number of therapeutic antibodies in development pipelines is increasing rapidly. Despite superior success rates relative to small molecules, therapeutic antibodies still face many unique development challenges. There is often a translational gap from their high target affinity and specificity to...

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Detalles Bibliográficos
Autores principales: Dunlap, Tyler, Cao, Yanguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912916/
https://www.ncbi.nlm.nih.gov/pubmed/35281913
http://dx.doi.org/10.3389/fphar.2022.856961