Cargando…

Small proline-rich proteins (SPRRs) are epidermally produced antimicrobial proteins that defend the cutaneous barrier by direct bacterial membrane disruption

Human skin functions as a physical barrier, preventing the entry of foreign pathogens while also accommodating a myriad of commensal microorganisms. A key contributor to the skin landscape is the sebaceous gland. Mice devoid of sebocytes are prone to skin infection, yet our understanding of how sebo...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chenlu, Hu, Zehan, Lone, Abdul G, Artami, Methinee, Edwards, Marshall, Zouboulis, Christos C, Stein, Maggie, Harris-Tryon, Tamia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912919/
https://www.ncbi.nlm.nih.gov/pubmed/35234613
http://dx.doi.org/10.7554/eLife.76729