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Small proline-rich proteins (SPRRs) are epidermally produced antimicrobial proteins that defend the cutaneous barrier by direct bacterial membrane disruption
Human skin functions as a physical barrier, preventing the entry of foreign pathogens while also accommodating a myriad of commensal microorganisms. A key contributor to the skin landscape is the sebaceous gland. Mice devoid of sebocytes are prone to skin infection, yet our understanding of how sebo...
Autores principales: | Zhang, Chenlu, Hu, Zehan, Lone, Abdul G, Artami, Methinee, Edwards, Marshall, Zouboulis, Christos C, Stein, Maggie, Harris-Tryon, Tamia A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912919/ https://www.ncbi.nlm.nih.gov/pubmed/35234613 http://dx.doi.org/10.7554/eLife.76729 |
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