Environmentally sensitive hotspots in the methylome of the early human embryo

In humans, DNA methylation marks inherited from gametes are largely erased following fertilisation, prior to construction of the embryonic methylome. Exploiting a natural experiment of seasonal variation including changes in diet and nutritional status in rural Gambia, we analysed three datasets cov...

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Detalles Bibliográficos
Autores principales: Silver, Matt J, Saffari, Ayden, Kessler, Noah J, Chandak, Gririraj R, Fall, Caroline HD, Issarapu, Prachand, Dedaniya, Akshay, Betts, Modupeh, Moore, Sophie E, Routledge, Michael N, Herceg, Zdenko, Cuenin, Cyrille, Derakhshan, Maria, James, Philip T, Monk, David, Prentice, Andrew M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912923/
https://www.ncbi.nlm.nih.gov/pubmed/35188105
http://dx.doi.org/10.7554/eLife.72031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912923/
https://www.ncbi.nlm.nih.gov/pubmed/35188105
http://dx.doi.org/10.7554/eLife.72031

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