Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo

The human endogenous retrovirus type-H (HERVH) family is expressed in the preimplantation embryo. A subset of these elements are specifically transcribed in pluripotent stem cells where they appear to exert regulatory activities promoting self-renewal and pluripotency. How HERVH elements achieve suc...

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Detalles Bibliográficos
Autores principales: Carter, Thomas A, Singh, Manvendra, Dumbović, Gabrijela, Chobirko, Jason D, Rinn, John L, Feschotte, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912925/
https://www.ncbi.nlm.nih.gov/pubmed/35179489
http://dx.doi.org/10.7554/eLife.76257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912925/
https://www.ncbi.nlm.nih.gov/pubmed/35179489
http://dx.doi.org/10.7554/eLife.76257

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