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In-depth Analysis of IS6110 Genomic Variability in the Mycobacterium tuberculosis Complex

The insertion sequence (IS) 6110 is a repetitive mobile element specific for the Mycobacterium tuberculosis complex (MTBC) used for years to diagnose and genotype this pathogen. It contains the overlapping reading frames orfA and orfB that encode a transposase. Its genetic variability is difficult t...

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Detalles Bibliográficos
Autores principales: Comín, Jessica, Otal, Isabel, Samper, Sofía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912993/
https://www.ncbi.nlm.nih.gov/pubmed/35283840
http://dx.doi.org/10.3389/fmicb.2022.767912