Feasibility study of a novel preparation strategy for anti-CD7 CAR-T cells with a recombinant anti-CD7 blocking antibody

Although chimeric antigen receptor (CAR) T cell immunotherapy has shown promising significance in B cell malignancies, success against T cell malignancies remains unsatisfactory because of shared antigenicity between normal and malignant T cells, resulting in fratricide and hindering CAR production...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Jia, Yujie, Tuhin, Israth Jahan, Tan, Jingwen, Monty, Masuma Akter, Xu, Nan, Kang, Liqing, Li, Minghao, Lou, Xiaoyan, Zhou, Meixia, Fang, Xiaoyan, Shao, Jiaqi, Zhu, Hongjia, Yan, Zhiqiang, Yu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913247/
https://www.ncbi.nlm.nih.gov/pubmed/35317521
http://dx.doi.org/10.1016/j.omto.2022.02.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913247/
https://www.ncbi.nlm.nih.gov/pubmed/35317521
http://dx.doi.org/10.1016/j.omto.2022.02.013

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