Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion

We previously reported that loss of mitochondrial transcription factor B1 (TFB1M) leads to mitochondrial dysfunction and is involved in the pathogenesis of type 2 diabetes (T2D). Whether defects in ribosomal processing impact mitochondrial function and could play a pathogenetic role in β-cells and T...

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Detalles Bibliográficos
Autores principales: Verma, Gaurav, Bowen, Alexander, Gheibi, Sevda, Hamilton, Alexander, Muthukumar, Sowndarya, Cataldo, Luis Rodrigo, Asplund, Olof, Esguerra, Jonathan, Karagiannopoulos, Alexandros, Lyons, Claire, Cowan, Elaine, Bellodi, Cristian, Prasad, Rashmi, Fex, Malin, Mulder, Hindrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913306/
https://www.ncbi.nlm.nih.gov/pubmed/35148993
http://dx.doi.org/10.1016/j.jbc.2022.101692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913306/
https://www.ncbi.nlm.nih.gov/pubmed/35148993
http://dx.doi.org/10.1016/j.jbc.2022.101692

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