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The tetrameric structure of Plasmodium falciparum phosphoglycerate mutase is critical for optimal enzymatic activity
The glycolytic enzyme phosphoglycerate mutase (PGM) is of utmost importance for overall cellular metabolism and has emerged as a novel therapeutic target in cancer cells. This enzyme is also conserved in the rapidly proliferating malarial parasite Plasmodium falciparum, which have a similar metaboli...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913309/ https://www.ncbi.nlm.nih.gov/pubmed/35150741 http://dx.doi.org/10.1016/j.jbc.2022.101713 |