The tetrameric structure of Plasmodium falciparum phosphoglycerate mutase is critical for optimal enzymatic activity

The glycolytic enzyme phosphoglycerate mutase (PGM) is of utmost importance for overall cellular metabolism and has emerged as a novel therapeutic target in cancer cells. This enzyme is also conserved in the rapidly proliferating malarial parasite Plasmodium falciparum, which have a similar metaboli...

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Detalles Bibliográficos
Autores principales: Tehlan, Ankita, Bhowmick, Krishanu, Kumar, Amarjeet, Subbarao, Naidu, Dhar, Suman Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913309/
https://www.ncbi.nlm.nih.gov/pubmed/35150741
http://dx.doi.org/10.1016/j.jbc.2022.101713

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