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Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE

Pseudomonas aeruginosa is a Gram-negative opportunistic human pathogen that is highly prevalent in individuals with cystic fibrosis (CF). A major problem in treating CF patients infected with P. aeruginosa is the development of antibiotic resistance. Therefore, the identification of novel P. aerugin...

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Detalles Bibliográficos
Autores principales: Tooker, Brian C., Kandel, Sylvie E., Work, Hannah M., Lampe, Jed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913318/
https://www.ncbi.nlm.nih.gov/pubmed/35085556
http://dx.doi.org/10.1016/j.jbc.2022.101629