Tafenoquine exhibits broad spectrum antifungal activity at clinically relevant concentrations in vitro and decreases lung fungal burden in an invasive pulmonary model of Rhizopus in vivo

BACKGROUND: Tafenoquine is active against a broad range of pathogens and accumulates extensively in the lung. We profiled the susceptibility of fungal pathogens to tafenoquine in vitro and in vivo. METHODS: Minimum inhibitory concentrations [MICs] of medically important fungal pathogens were determi...

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Detalles Bibliográficos
Autores principales: Dow, G., Smith, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913336/
https://www.ncbi.nlm.nih.gov/pubmed/35284080
http://dx.doi.org/10.1016/j.nmni.2022.100964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913336/
https://www.ncbi.nlm.nih.gov/pubmed/35284080
http://dx.doi.org/10.1016/j.nmni.2022.100964

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