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METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m(6)A-YTHDF2-dependent manner

N6-methyladenosine (m(6)A) RNA methylation has recently been found involving in regulatory mechanism of the tumor progression. Our aim was to explore the biological function and clinical significance of the m(6)A methyltransferase METTL3 in intrahepatic cholangiocarcinoma (ICC). In this study, we re...

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Detalles Bibliográficos
Autores principales: Xu, Qiong-Cong, Tien, Yi-Chih, Shi, Yin-Hao, Chen, Siyun, Zhu, Ying-Qin, Huang, Xi-Tai, Huang, Chen-Song, Zhao, Wei, Yin, Xiao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913368/
https://www.ncbi.nlm.nih.gov/pubmed/35094011
http://dx.doi.org/10.1038/s41388-022-02185-1