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Effect of dose adjustments on the efficacy and safety of tofacitinib in patients with rheumatoid arthritis: a post hoc analysis of an open-label, long-term extension study (ORAL Sequel)

INTRODUCTION/OBJECTIVES: We assess the impact of switching versus staying on the same tofacitinib dose on efficacy and safety in patients with rheumatoid arthritis (RA). METHODS: ORAL Sequel was an open-label, long-term extension study of patients with RA receiving tofacitinib 5 or 10 mg BID for up...

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Detalles Bibliográficos
Autores principales: Mueller, Ruediger B., Schulze-Koops, Hendrik, Furst, Daniel E., Cohen, Stanley B. , Kwok, Kenneth, Wang, Lisy, Killeen, Tim, von Kempis, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913559/
https://www.ncbi.nlm.nih.gov/pubmed/34973077
http://dx.doi.org/10.1007/s10067-021-05908-z