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Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity

Human noroviruses (HuNoVs) cause sporadic and epidemic viral gastroenteritis worldwide. The GII.4 variants are responsible for most HuNoV infections, and GII.4 virus-like particles (VLPs) are being used in vaccine development. The atomic structure of the GII.4 capsid in the native T = 3 state has no...

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Detalles Bibliográficos
Autores principales: Hu, Liya, Salmen, Wilhelm, Chen, Rong, Zhou, Yi, Neill, Frederick, Crowe, James E., Atmar, Robert L., Estes, Mary K., Prasad, B. V. Venkataram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913647/
https://www.ncbi.nlm.nih.gov/pubmed/35273142
http://dx.doi.org/10.1038/s41467-022-28757-z