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SIAH1 reverses chemoresistance in epithelial ovarian cancer via ubiquitination of YBX-1

Chemoresistance is a severe outcome among patients with epithelial ovarian cancer (EOC) that leads to a poor prognosis. YBX-1 has been shown to cause treatment failure and cancer progression in EOC. However, strategies that directly target YBX-1 are not yet conceivable. Here, we identified that SIAH...

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Detalles Bibliográficos
Autores principales: Gao, Wujiang, Chen, Lu, Lin, Li, Yang, Meiling, Li, Taoqiong, Wei, Hong, Sha, Chunli, Xing, Jie, Zhang, Mengxue, Zhao, Shijie, Chen, Qi, Xu, Wenlin, Li, Yuefeng, Zhu, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913663/
https://www.ncbi.nlm.nih.gov/pubmed/35273154
http://dx.doi.org/10.1038/s41389-022-00387-6