A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike

Current SARS-CoV-2 vaccines are effective, but long-term protection is threatened by the emergence of virus variants. We generated a virosome vaccine containing the Beta spike protein and compared its immunogenicity in mice to a virosome vaccine containing the original Wuhan spike. Two administratio...

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Detalles Bibliográficos
Autores principales: van der Velden, Yme U., Grobben, Marloes, Caniels, Tom G., Burger, Judith A., Poniman, Meliawati, Oomen, Melissa, Rijnstra, Esther Siteur-van, Tejjani, Khadija, Guerra, Denise, Kempers, Ronald, Stegmann, Toon, van Gils, Marit J., Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913678/
https://www.ncbi.nlm.nih.gov/pubmed/35273217
http://dx.doi.org/10.1038/s41598-022-07590-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913678/
https://www.ncbi.nlm.nih.gov/pubmed/35273217
http://dx.doi.org/10.1038/s41598-022-07590-w

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