Cargando…
A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike
Current SARS-CoV-2 vaccines are effective, but long-term protection is threatened by the emergence of virus variants. We generated a virosome vaccine containing the Beta spike protein and compared its immunogenicity in mice to a virosome vaccine containing the original Wuhan spike. Two administratio...
Autores principales: | van der Velden, Yme U., Grobben, Marloes, Caniels, Tom G., Burger, Judith A., Poniman, Meliawati, Oomen, Melissa, Rijnstra, Esther Siteur-van, Tejjani, Khadija, Guerra, Denise, Kempers, Ronald, Stegmann, Toon, van Gils, Marit J., Sanders, Rogier W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913678/ https://www.ncbi.nlm.nih.gov/pubmed/35273217 http://dx.doi.org/10.1038/s41598-022-07590-w |
Ejemplares similares
-
A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern
por: Brinkkemper, Mitch, et al.
Publicado: (2021) -
Co-display of diverse spike proteins on nanoparticles broadens sarbecovirus neutralizing antibody responses
por: Brinkkemper, Mitch, et al.
Publicado: (2022) -
Early Effects of HTLV-1 Infection on the Activation, Exhaustion, and Differentiation of T-Cells in Humanized NSG Mice
por: Espíndola, Otávio de Melo, et al.
Publicado: (2021) -
Insect Cells for High-Yield Production of SARS-CoV-2 Spike Protein: Building a Virosome-Based COVID-19 Vaccine Candidate
por: Fernandes, Bárbara, et al.
Publicado: (2022) -
Diverse HIV-1 escape pathways from broadly neutralizing antibody PGDM1400 in humanized mice
por: van der Velden, Yme U., et al.
Publicado: (2020)