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Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture

G protein-coupled receptors (GPCRs) form the largest family of cell surface receptors. Despite considerable insights into their pharmacology, the GPCR architecture at the cell surface still remains largely unexplored. Herein, we present the specific unfolding of different GPCRs at the surface of liv...

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Detalles Bibliográficos
Autores principales: Dague, Etienne, Pons, Véronique, Roland, Alexandre, Azaïs, Jean-Marc, Arcucci, Silvia, Lachaize, Véronique, Velmont, Samuel, Trevisiol, Emmanuelle, N’Guyen, Du, Sénard, Jean-Michel, Galés, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913689/
https://www.ncbi.nlm.nih.gov/pubmed/35273337
http://dx.doi.org/10.1038/s42003-022-03162-w