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Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture
G protein-coupled receptors (GPCRs) form the largest family of cell surface receptors. Despite considerable insights into their pharmacology, the GPCR architecture at the cell surface still remains largely unexplored. Herein, we present the specific unfolding of different GPCRs at the surface of liv...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913689/ https://www.ncbi.nlm.nih.gov/pubmed/35273337 http://dx.doi.org/10.1038/s42003-022-03162-w |