New AKT-dependent mechanisms of anti-COVID-19 action of high-CBD Cannabis sativa extracts

COVID-19 is caused by the SARS-CoV-2 virus, which enters target cells via interactions with ACE2 and TMPRSS2. Here, we show AKT serine/threonine kinase-dependent epigenetic control of ACE2 and TMPRSS2 expression by high-cannabidiol (CBD) cannabis extracts and their individual components. CBD alone a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Dongping, Fiselier, Anna, Kovalchuk, Igor, Kovalchuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913855/
https://www.ncbi.nlm.nih.gov/pubmed/35277472
http://dx.doi.org/10.1038/s41420-022-00876-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913855/
https://www.ncbi.nlm.nih.gov/pubmed/35277472
http://dx.doi.org/10.1038/s41420-022-00876-y

Ejemplares similares