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Ionizing Radiation-Induced GDF15 Promotes Angiogenesis in Human Glioblastoma Models by Promoting VEGFA Expression Through p-MAPK1/SP1 Signaling

Glioblastoma multiforme (GBM), the most aggressive cancer type that has a poor prognosis, is characterized by enhanced and aberrant angiogenesis. In addition to surgical resection and chemotherapy, radiotherapy is commonly used to treat GBM. However, radiation-induced angiogenesis in GBM remains une...

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Detalles Bibliográficos
Autores principales: Park, Hyejin, Nam, Ki-Seok, Lee, Hae-June, Kim, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913883/
https://www.ncbi.nlm.nih.gov/pubmed/35280749
http://dx.doi.org/10.3389/fonc.2022.801230