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Lower Levels of GABAergic Function Markers in Corticotropin-Releasing Hormone-Expressing Neurons in the sgACC of Human Subjects With Depression

RATIONALE: A previous transcriptome meta-analysis revealed significantly lower levels of corticotropin-releasing hormone (CRH) mRNA in corticolimbic brain regions in major depressive disorder (MDD) subjects, suggesting that cortical CRH-expressing (CRH+) cells are affected in MDD. Rodent studies sho...

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Detalles Bibliográficos
Autores principales: Oh, Hyunjung, Newton, Dwight, Lewis, David, Sibille, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913899/
https://www.ncbi.nlm.nih.gov/pubmed/35280164
http://dx.doi.org/10.3389/fpsyt.2022.827972