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Tim-3 Blockade Elicits Potent Anti-Multiple Myeloma Immunity of Natural Killer Cells

Multiple myeloma (MM) is still an incurable plasma cell tumor. Natural killer (NK) cells are characterized by efficient anti-tumor activity, and their activity is one basis of cancer immunotherapeutic strategies. Tim-3, one of the immune checkpoint molecules, negatively regulates NK cell activity. T...

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Detalles Bibliográficos
Autores principales: Jiang, Wen, Li, Fanglin, Jiang, Yang, Li, Shengli, Liu, Xiaoli, Xu, Yaqi, Li, Binggen, Feng, Xiaoli, Zheng, Chengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913933/
https://www.ncbi.nlm.nih.gov/pubmed/35280800
http://dx.doi.org/10.3389/fonc.2022.739976