Cargando…
Tim-3 Blockade Elicits Potent Anti-Multiple Myeloma Immunity of Natural Killer Cells
Multiple myeloma (MM) is still an incurable plasma cell tumor. Natural killer (NK) cells are characterized by efficient anti-tumor activity, and their activity is one basis of cancer immunotherapeutic strategies. Tim-3, one of the immune checkpoint molecules, negatively regulates NK cell activity. T...
Autores principales: | Jiang, Wen, Li, Fanglin, Jiang, Yang, Li, Shengli, Liu, Xiaoli, Xu, Yaqi, Li, Binggen, Feng, Xiaoli, Zheng, Chengyun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913933/ https://www.ncbi.nlm.nih.gov/pubmed/35280800 http://dx.doi.org/10.3389/fonc.2022.739976 |
Ejemplares similares
-
PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells
por: Guo, Yanan, et al.
Publicado: (2016) -
Targeting Tim-3 in Cancer With Resistance to PD-1/PD-L1 Blockade
por: Tian, Tian, et al.
Publicado: (2021) -
Telomere length is positively associated with the expression of IL-6 and MIP-1α in bone marrow mesenchymal stem cells of multiple myeloma
por: Li, Shengli, et al.
Publicado: (2017) -
Novel Small Molecular Compound AE-848 Potently Induces Human Multiple Myeloma Cell Apoptosis by Modulating the NF-κB and PI3K/Akt/mTOR Signaling Pathways
por: Xu, Yaqi, et al.
Publicado: (2020) -
Human induced-T-to-natural killer cells have potent anti-tumour activities
por: Jiang, Zhiwu, et al.
Publicado: (2022)