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Conformational Dynamics of DNA Polymerases Revealed at the Single-Molecule Level
DNA polymerases are intrinsically dynamic macromolecular machines. The purpose of this review is to describe the single-molecule Förster resonance energy transfer (smFRET) methods that are used to probe the conformational dynamics of DNA polymerases, focusing on E. coli DNA polymerase I. The studies...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913937/ https://www.ncbi.nlm.nih.gov/pubmed/35281261 http://dx.doi.org/10.3389/fmolb.2022.826593 |