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Common Variation in EDN1 Regulatory Regions Highlights the Role of PPARγ as a Key Regulator of Endothelin in vitro

Pulmonary Arterial Hypertension (PAH) is a rare disease caused by the obliteration of the pulmonary arterioles, increasing pulmonary vascular resistance and eventually causing right heart failure. Endothelin-1 (EDN1) is a vasoconstrictor peptide whose levels are indicators of disease progression and...

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Detalles Bibliográficos
Autores principales: Lago-Docampo, Mauro, Solarat, Carlos, Méndez-Martínez, Luis, Baloira, Adolfo, Valverde, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913939/
https://www.ncbi.nlm.nih.gov/pubmed/35282351
http://dx.doi.org/10.3389/fcvm.2022.823133