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Excessive Activation of Notch Signaling in Macrophages Promote Kidney Inflammation, Fibrosis, and Necroptosis

Diabetic nephropathy (DN) is one of the main causes of end-stage renal disease (ESRD). Existing treatments cannot control the progression of diabetic nephropathy very well. In diabetic nephropathy, Many monocytes and macrophages infiltrate kidney tissue. However, the role of these cells in the patho...

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Detalles Bibliográficos
Autores principales: Ma, Tiankui, Li, Xin, Zhu, Yonghong, Yu, Shufan, Liu, Tianyan, Zhang, Xiaodan, Chen, Dong, Du, Shuyan, Chen, Tong, Chen, Shuo, Xu, Yanyan, Fan, Qiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913942/
https://www.ncbi.nlm.nih.gov/pubmed/35280997
http://dx.doi.org/10.3389/fimmu.2022.835879