An in Silico Approach to Reveal the Nanodisc Formulation of Doxorubicin

Molecular dynamic behaviors of nanodisc (ND) formulations of free doxorubicin (DOX) and DOX conjugated lipid prodrug molecules were investigated by molecular dynamics (MD) simulations. We have unveiled how formulation design affects the drug release profile and conformational stability of ND assembl...

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Detalles Bibliográficos
Autores principales: Xu, Daiyun, Chen, Xu, Chen, Zhidong, Lv, Yonghui, Li, Yongxiao, Li, Shengbin, Xu, Wanting, Mo, Yuan, Wang, Xinpei, Chen, Zirui, Chen, Tingyi, Wang, Tianqi, Wang, Zhe, Wu, Meiying, Wang, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914043/
https://www.ncbi.nlm.nih.gov/pubmed/35284419
http://dx.doi.org/10.3389/fbioe.2022.859255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914043/
https://www.ncbi.nlm.nih.gov/pubmed/35284419
http://dx.doi.org/10.3389/fbioe.2022.859255

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