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Structure-Activity Relationship (SAR) Model for Predicting Teratogenic Risk of Antiseizure Medications in Pregnancy by Using Support Vector Machine

Teratogenicity is one of the main concerns in clinical medications of pregnant women. Prescription of antiseizure medications (ASMs) in women with epilepsy during pregnancy may cause teratogenic effects on the fetus. Although large scale epilepsy pregnancy registries played an important role in eval...

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Detalles Bibliográficos
Autores principales: Kang, Liyuan, Duan, Yifei, Chen, Cheng, Li, Shihai, Li, Menglong, Chen, Lei, Wen, Zhining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914116/
https://www.ncbi.nlm.nih.gov/pubmed/35281912
http://dx.doi.org/10.3389/fphar.2022.747935