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A single amino acid exchange converts FocA into a unidirectional efflux channel for formate
During mixed-acid fermentation, Escherichia coli initially translocates formate out of the cell, but re-imports it at lower pH. This is performed by FocA, the archetype of the formate-nitrite transporter (FNT) family of pentameric anion channels. Each protomer of FocA has a hydrophobic pore through...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Microbiology Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914244/ https://www.ncbi.nlm.nih.gov/pubmed/35084298 http://dx.doi.org/10.1099/mic.0.001132 |